Hello,
With Python 3.11, I get "unable to open database file" quite quickly and "easily".
It turns out that my app has way too many "cache.db" opened. This looks like a leak, I tried to build a simple reproducer without any success yet.
I'm not sure how to track this down, it seems related to using diskcache from PySide 6 threads (QThread).
Could this be related to python/cpython#97641 and python/cpython#108015 ?
Do you have any idea how to investigate or better to solve this 😅?

The thread is implemented here and here in another package is the shared diskcache wrapper that seems to leak file descriptors.