Why did you removed defined(STM32U0xx) ?

Actually, I did not remove it either.

It was not in my version of that file. I will make the correction.

Hi @drmcnelson
Sorry for the delay looking at this PR.

In fact there is a mistake. Using LL_SPI_TransmitData16 is not enough to properly transfer 16bit.

It requires to configure the data size to SPI_DATASIZE_16BIT.

So it should require to manage it.
Several way:

1. Adding below code in spi_transfer16 (same for the spi_transfer with LL_SPI_DATAWIDTH_8BIT

  if (LL_SPI_GetDataWidth(_SPI) != LL_SPI_DATAWIDTH_16BIT) {
    /* Change data width to 16 bit */
    LL_SPI_Disable(_SPI);
    LL_SPI_SetDataWidth(_SPI, LL_SPI_DATAWIDTH_16BIT);
    LL_SPI_Enable(_SPI);
  }

This add at least 1 check per transfer.

2. Kept transfer16 as it is and add a 2 new API, one to change the size and one to call LL_SPI_TransmitData16.

3. Add an API to change the data size before calling the transfer16 but this will break all Arduino sketches.

4. maybe other way...

@fpistm Wonderful, thank you, and thank for you looking at it.

How about a variable transfer size? Some ADCs are 18 bit (or larger) and some are daisy-chainable, so that transfers could be several times 18 bits (or larger). I have been doing this by hand for an acoustic imaging array, but with the new world of 32 bit processors and higher precision preripherals, maybe it's time to upgrade the SPI interface for everybody.