| Caffeine withdrawal | |
|---|---|
 | |
| Molecular structure of caffeine | |
| Specialty | Psychiatry |
| Symptoms | Headache, fatigue or drowsiness, depression, irritability, difficulty concentrating, nausea or vomiting |
| Usual onset | 12–48 hours after the last use |
| Duration | Up to 7 days |
Caffeine withdrawal is a set of symptoms, behaviors, and physiological changes that can occur when an individual significantly reduces or stops consuming caffeine. This condition typically arises in individuals who have regularly consumed caffeine over an extended period or in substantial amounts. Common sources of caffeine include coffee, tea, energy drinks, and certain over-the-counter medications.
"ICD-11 for Mortality and Morbidity Statistics: 6C48.3 Caffeine withdrawal". World Health Organization. Retrieved 2025-03-13.