In [1]: # tuple-based

In [2]: %timeit 'a' in ('a', 'b', 'c', 'd', 'e', 'f', 'g')
9.91 ns ± 0.0982 ns per loop (mean ± std. dev. of 7 runs, 100,000,000 loops each)

In [3]: %timeit 'd' in ('a', 'b', 'c', 'd', 'e', 'f', 'g')
33.2 ns ± 0.701 ns per loop (mean ± std. dev. of 7 runs, 10,000,000 loops each)

In [4]: %timeit 'g' in ('a', 'b', 'c', 'd', 'e', 'f', 'g')
56.4 ns ± 0.818 ns per loop (mean ± std. dev. of 7 runs, 10,000,000 loops each)

In [5]: # set-based

In [6]: %timeit 'a' in {'a', 'b', 'c', 'd', 'e', 'f', 'g'}
11.3 ns ± 0.0723 ns per loop (mean ± std. dev. of 7 runs, 100,000,000 loops each)

In [7]: %timeit 'd' in {'a', 'b', 'c', 'd', 'e', 'f', 'g'}
11 ns ± 0.106 ns per loop (mean ± std. dev. of 7 runs, 100,000,000 loops each)

In [8]: %timeit 'g' in {'a', 'b', 'c', 'd', 'e', 'f', 'g'}
11.1 ns ± 0.126 ns per loop (mean ± std. dev. of 7 runs, 100,000,000 loops each)

from contextlib import suppress
from dataclasses import FrozenInstanceError, dataclass

@dataclass(frozen=True)
class Foo2:
    a: int
    b: int

foo2 = Foo2(1, 2)

def bench2(inst):
    with suppress(FrozenInstanceError):
        inst.a = 0
    with suppress(FrozenInstanceError):
        inst.b = 0

@dataclass(frozen=True)
class Foo7:
    a: int
    b: int
    c: int
    d: int
    e: int
    f: int
    g: int

foo7 = Foo7(1, 2, 3, 4, 5, 6, 7)

def bench7(inst):
    with suppress(FrozenInstanceError):
        inst.a = 0
    with suppress(FrozenInstanceError):
        inst.b = 0
    with suppress(FrozenInstanceError):
        inst.c = 0
    with suppress(FrozenInstanceError):
        inst.d = 0
    with suppress(FrozenInstanceError):
        inst.e = 0
    with suppress(FrozenInstanceError):
        inst.f = 0
    with suppress(FrozenInstanceError):
        inst.g = 0

class Bar(Foo7):
    def __init__(self, a, b, c, d, e, f, g):
        super().__init__(a, b, c, d, e, f, g)
        self.baz = 0

def bench(inst):
    inst.baz = 1

In [2]: %timeit bench2(foo2)
1.08 µs ± 28.1 ns per loop (mean ± std. dev. of 7 runs, 1,000,000 loops each)

In [3]: %timeit bench7(foo7)
3.81 µs ± 20.3 ns per loop (mean ± std. dev. of 7 runs, 100,000 loops each)

In [4]: %timeit bench(bar)
249 ns ± 6.31 ns per loop (mean ± std. dev. of 7 runs, 1,000,000 loops each)

In [2]: %timeit bench2(foo2)
1.15 µs ± 10.9 ns per loop (mean ± std. dev. of 7 runs, 1,000,000 loops each)

In [3]: %timeit bench7(foo7)
3.97 µs ± 15.7 ns per loop (mean ± std. dev. of 7 runs, 100,000 loops each)

In [4]: %timeit bench(bar)
269 ns ± 4.09 ns per loop (mean ± std. dev. of 7 runs, 1,000,000 loops each)