diff --git a/Lib/test/test_tools/test_sundry.py b/Lib/test/test_tools/test_sundry.py
@@ -25,7 +25,7 @@ class TestSundryScripts(unittest.TestCase):
     # scripts that use windows-only modules
     windows_only = ['win_add2path']
     # denylisted for other reasons
-    other = ['analyze_dxp', '2to3']
+    other = ['2to3']
 
     skiplist = denylist + allowlist + windows_only + other
 
@@ -50,13 +50,6 @@ def test_sundry_windows(self):
         for name in self.windows_only:
             import_tool(name)
 
-    def test_analyze_dxp_import(self):
-        if hasattr(sys, 'getdxp'):
-            import_tool('analyze_dxp')
-        else:
-            with self.assertRaises(RuntimeError):
-                import_tool('analyze_dxp')
-
 
 if __name__ == '__main__':
     unittest.main()
diff --git a/Misc/NEWS.d/next/Core and Builtins/2022-09-30-13-26-58.gh-issue-97670.n61vMR.rst b/Misc/NEWS.d/next/Core and Builtins/2022-09-30-13-26-58.gh-issue-97670.n61vMR.rst
@@ -0,0 +1,6 @@
+Remove the :func:`sys.getdxp` function and the ``Tools/scripts/analyze_dxp.py``
+script. DXP stands for "dynamic execution pairs". They were related to
+``DYNAMIC_EXECUTION_PROFILE`` and ``DXPAIRS`` macros which have been removed in
+Python 3.11. Python can now be built with :option:`./configure --enable-pystats
+<--enable-pystats>` to gather statistics on Python opcodes.  Patch by Victor
+Stinner.
@@ -7207,61 +7207,6 @@ format_awaitable_error(PyThreadState *tstate, PyTypeObject *type, int oparg)
     }
 }
 
-#ifdef Py_STATS
-
-static PyObject *
-getarray(uint64_t a[256])
-{
-    int i;
-    PyObject *l = PyList_New(256);
-    if (l == NULL) return NULL;
-    for (i = 0; i < 256; i++) {
-        PyObject *x = PyLong_FromUnsignedLongLong(a[i]);
-        if (x == NULL) {
-            Py_DECREF(l);
-            return NULL;
-        }
-        PyList_SET_ITEM(l, i, x);
-    }
-    for (i = 0; i < 256; i++)
-        a[i] = 0;
-    return l;
-}
-
-PyObject *
-_Py_GetDXProfile(PyObject *self, PyObject *args)
-{
-    int i;
-    PyObject *l = PyList_New(257);
-    if (l == NULL) return NULL;
-    for (i = 0; i < 256; i++) {
-        PyObject *x = getarray(_py_stats_struct.opcode_stats[i].pair_count);
-        if (x == NULL) {
-            Py_DECREF(l);
-            return NULL;
-        }
-        PyList_SET_ITEM(l, i, x);
-    }
-    PyObject *counts = PyList_New(256);
-    if (counts == NULL) {
-        Py_DECREF(l);
-        return NULL;
-    }
-    for (i = 0; i < 256; i++) {
-        PyObject *x = PyLong_FromUnsignedLongLong(
-            _py_stats_struct.opcode_stats[i].execution_count);
-        if (x == NULL) {
-            Py_DECREF(counts);
-            Py_DECREF(l);
-            return NULL;
-        }
-        PyList_SET_ITEM(counts, i, x);
-    }
-    PyList_SET_ITEM(l, 256, counts);
-    return l;
-}
-
-#endif
 
 Py_ssize_t
 _PyEval_RequestCodeExtraIndex(freefunc free)

@@ -2014,11 +2014,6 @@ sys__debugmallocstats_impl(PyObject *module)
 extern PyObject *_Py_GetObjects(PyObject *, PyObject *);
 #endif
 
-#ifdef Py_STATS
-/* Defined in ceval.c because it uses static globals in that file */
-extern PyObject *_Py_GetDXProfile(PyObject *,  PyObject *);
-#endif
-
 #ifdef __cplusplus
 }
 #endif
@@ -2217,9 +2212,6 @@ static PyMethodDef sys_methods[] = {
     SYS_GETDEFAULTENCODING_METHODDEF
     SYS_GETDLOPENFLAGS_METHODDEF
     SYS_GETALLOCATEDBLOCKS_METHODDEF
-#ifdef Py_STATS
-    {"getdxp", _Py_GetDXProfile, METH_VARARGS},
-#endif
     SYS_GETFILESYSTEMENCODING_METHODDEF
     SYS_GETFILESYSTEMENCODEERRORS_METHODDEF
     SYS__GETQUICKENEDCOUNT_METHODDEF

diff --git a/Tools/scripts/README b/Tools/scripts/README
@@ -3,7 +3,6 @@ useful while building, extending or managing Python.
 
 2to3                      Main script for running the 2to3 conversion tool
 abitype.py                Converts a C file to use the PEP 384 type definition API
-analyze_dxp.py            Analyzes the result of sys.getdxp()
 combinerefs.py            A helper for analyzing PYTHONDUMPREFS output
 diff.py                   Print file diffs in context, unified, or ndiff formats
 eptags.py                 Create Emacs TAGS file for Python modules

diff --git a/Tools/scripts/analyze_dxp.py b/Tools/scripts/analyze_dxp.py