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lehner-lab/Programmed_readthrough: Programmed translational readthrough produces C-terminally extended protein isoforms via decoding of stop codons by near-cognate tRNAs. Here we use deep mutational scanning to quantify ~1,400 sequence variants for each of the three examples of human readthrough in the genes AQP4, MAPK10 and OPRK1. · GitHub

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Programmed_readthrough

Programmed translational readthrough produces C-terminally extended protein isoforms via decoding of stop codons by near-cognate tRNAs. Here we use deep mutational scanning to quantify ~1,400 sequence variants for each of the three examples of human readthrough in the genes AQP4, MAPK10 and OPRK1.

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Programmed translational readthrough produces C-terminally extended protein isoforms via decoding of stop codons by near-cognate tRNAs. Here we use deep mutational scanning to quantify ~1,400 sequence variants for each of the three examples of human readthrough in the genes AQP4, MAPK10 and OPRK1.

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